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While we observe clear changes in neural function as a direct result of prolonged TNF-α and IL-6 exposures in human-relevant co-cultures of neurons and astrocytes, the limitation of this model is that it is without microglia, the innate immune cell of the brain

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Water quality can be one of those practical factors: if tap water has a noticeable odor, taste, or mineral profile, some people end up drinking less without realizing it